SCHEMBL8550866

SCHEMBL8550866

Cn1nc(Cl)n(-c2cc(NS(=O)(=O)CCl)c(Cl)cc2F)c1=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 1/20 0.39
PPOX P50336 1/20 0.36
MAPT P10636 1/20 0.32
BRD4 O60885 1/20 0.31
NMT1 P30419 1/20 0.30
MCL1 Q07820 1/20 0.30
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8096523 0.78 PPOX (0.33) PPOXMAPTBRD4
SCHEMBL8129933 0.75 PPOX (0.66) PPOX
SCHEMBL8553485 0.74 BRD9 (0.40) BRD9
SCHEMBL8551425 0.70 BRD9 (0.40) BRD9L3MBTL1KMT2A
SCHEMBL7901426 0.69 MCL1 (0.32) MCL1
SCHEMBL4677597 0.69 PPOX (0.33) PPOXMAPTBRD4
SCHEMBL7833797 0.69 PSIP1 (0.33) PPOXMAPTBRD4
SCHEMBL6202490 0.69 KMT2A (0.38) KMT2A
SCHEMBL144307 0.68 EGLN1 (0.34) PPOX
SCHEMBL29367340 0.68 EGLN1 (0.34) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863142-A1 Heterocyclic herbicides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-09 EP claimed
EP-0863142-A1 Heterocyclic herbicides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-09 EP disclosed