Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552270 | 0.90 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3OPRK1CYP2D6 | |
| SCHEMBL8553707 | 0.88 | CCR5 (0.48) | OPRK1CYP2D6CCR5OPRM1OPRD1 | |
| SCHEMBL8547882 | 0.86 | CCR5 (0.43) | SLC6A2SLC6A4OPRK1CYP2D6CCR5 | |
| SCHEMBL8550877 | 0.85 | CCR5 (0.51) | SIGMAR1OPRK1CYP2D6CCR5OPRM1 | |
| SCHEMBL8552457 | 0.81 | CCR5 (0.48) | SIGMAR1OPRK1CYP2D6CCR5OPRM1 | |
| SCHEMBL8551862 | 0.79 | TACR1 (0.41) | OPRK1CYP2D6CCR5OPRM1OPRD1 | |
| SCHEMBL8476568 | 0.75 | CCR5 (0.43) | SIGMAR1OPRK1CYP2D6CCR5OPRM1 | |
| SCHEMBL6979619 | 0.75 | OPRK1 (0.55) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6979616 | 0.75 | OPRK1 (0.55) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL9098158 | 0.73 | CCR5 (0.49) | SIGMAR1OPRK1CYP2D6CCR5OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | claimed |