⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146143 | 0.71 | KIF11 (0.43) | — | |
| SCHEMBL7079413 | 0.69 | MEN1 (0.41) | — | |
| SCHEMBL28983414 | 0.63 | ALOX15 (0.52) | — | |
| SCHEMBL8550975 | 0.62 | POLB (0.43) | — | |
| SCHEMBL24726998 | 0.62 | HTR7 (0.39) | — | |
| SCHEMBL20725511 | 0.61 | GABRP (0.43) | — | |
| SCHEMBL16311858 | 0.60 | MEN1 (0.36) | — | |
| SCHEMBL20083348 | 0.59 | KDM4E (0.30) | — | |
| SCHEMBL24633146 | 0.59 | GPR3 (0.33) | — | |
| SCHEMBL23863477 | 0.59 | MAPT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832650-A2 | Use of serotonin 5-HT1F agonists for the prevention of migraine | ELI LILLY AND COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0824917-A2 | Use of a serotonin 5-HTlf agonist in the manufacture of a medicament for treating or ameliorating the symptoms of common cold or allergic rhinitis | ELI LILLY AND COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |