Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550897 | 0.85 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL8551790 | 0.76 | MAPT (0.39) | TGM2MEN1KMT2A | |
| SCHEMBL8150989 | 0.75 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1TSHRPTGESALOX5 | |
| SCHEMBL8551807 | 0.75 | TGM2 (0.43) | TGM2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8547481 | 0.75 | TGM2 (0.43) | TGM2SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL8545460 | 0.74 | ALDH1A1 (0.34) | TGM2SMN1; SMN2KMT2AALDH1A1TSHR | |
| SCHEMBL8158313 | 0.73 | ALOX5 (0.35) | SMN1; SMN2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8549387 | 0.71 | DPEP1 (0.42) | MEN1KMT2AEGFR | |
| SCHEMBL8553931 | 0.71 | DPEP1 (0.42) | TGM2EGFRALDH1A1TSHRMAPK1 | |
| SCHEMBL8157433 | 0.71 | APEX1 (0.39) | SMN1; SMN2ALDH1A1TSHRTDP1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |