Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552907 | 0.85 | ALDH1A1 (0.47) | AKR1C3MMP1MMP2MMP9FBP1 | |
| SCHEMBL8551807 | 0.84 | TGM2 (0.43) | MAPTMTNR1AMTNR1BTGM2MEN1 | |
| SCHEMBL8545460 | 0.84 | ALDH1A1 (0.34) | MAPTMTNR1AMTNR1BTGM2KMT2A | |
| SCHEMBL8550868 | 0.83 | AKR1C3 (0.43) | MAPTAKR1C3AKR1C2FBP1EPHX2 | |
| SCHEMBL8549387 | 0.81 | DPEP1 (0.42) | MEN1KMT2A | |
| SCHEMBL8553931 | 0.81 | DPEP1 (0.42) | TGM2 | |
| SCHEMBL9408933 | 0.79 | PYGL (0.50) | — | |
| SCHEMBL9408949 | 0.78 | ZDHHC20 (0.42) | TGM2 | |
| SCHEMBL1655139 | 0.77 | RECQL (0.50) | MAPTAKR1C3AKR1C2MMP1MMP2 | |
| SCHEMBL31293405 | 0.77 | RECQL (0.50) | MAPTAKR1C3AKR1C2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |