Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.31 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.31 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551388 | 0.85 | TGM2 (0.41) | SMN1; SMN2MEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL8158313 | 0.79 | ALOX5 (0.35) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8550868 | 0.78 | AKR1C3 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8552707 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9ACYP3A4 | |
| SCHEMBL8157433 | 0.77 | APEX1 (0.39) | SMN1; SMN2ALDH1A1NPC1RAB9APTGES | |
| SCHEMBL8550399 | 0.77 | ALDH1A1 (0.41) | SMN1; SMN2MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8552120 | 0.76 | RAB9A (0.35) | SMN1; SMN2MEN1PKMKMT2AL3MBTL1 | |
| SCHEMBL8554588 | 0.76 | TRPA1 (0.38) | SMN1; SMN2MEN1PKMKMT2AALDH1A1 | |
| SCHEMBL8548079 | 0.76 | CA1 (0.41) | ALDH1A1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8551274 | 0.75 | PLAAT3 (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |