Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551509 | 0.90 | SIGMAR1 (0.39) | SLC6A2SLC6A4CCR5CACNA2D1CACNA1B | |
| SCHEMBL8547882 | 0.86 | CCR5 (0.43) | SLC6A2SLC6A4CCR5CACNA2D1CACNA1B | |
| SCHEMBL8553707 | 0.84 | CCR5 (0.48) | CCR5CACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL8550877 | 0.83 | CCR5 (0.51) | CCR5OPRK1CYP2D6CYP3A4OPRM1 | |
| SCHEMBL8552457 | 0.80 | CCR5 (0.48) | CCR5OPRK1CYP2D6TACR1OPRM1 | |
| SCHEMBL8551862 | 0.77 | TACR1 (0.41) | CCR5OPRK1CYP2D6TACR1OPRM1 | |
| SCHEMBL6973106 | 0.76 | OPRK1 (0.53) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6973107 | 0.76 | OPRK1 (0.53) | CCR5OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL8476568 | 0.74 | CCR5 (0.43) | CCR5OPRK1CYP2D6CYP3A4TACR1 | |
| SCHEMBL8552339 | 0.73 | NOTUM (0.44) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | claimed |
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | disclosed |