Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893125 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2KMT2AMEN1CYP1A2TP53 | |
| SCHEMBL8553674 | 0.81 | P2RY1 (0.37) | SMN1; SMN2KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL20481554 | 0.78 | P2RY1 (0.39) | SMN1; SMN2KMT2AMEN1TP53RAB9A | |
| SCHEMBL8552542 | 0.76 | RAB9A (0.47) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8555203 | 0.76 | P2RY1 (0.43) | SMN1; SMN2KMT2ANPC1ALDH1A1HPGD | |
| SCHEMBL8553290 | 0.74 | LRRK2 (0.49) | SMN1; SMN2KMT2AMEN1CYP1A2RAB9A | |
| SCHEMBL12195699 | 0.74 | RIPK1 (0.36) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9224524 | 0.72 | P2RY1 (0.43) | SMN1; SMN2KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL8553127 | 0.72 | MEN1 (0.39) | SMN1; SMN2KMT2AMEN1CYP1A2ALDH1A1 | |
| SCHEMBL8551449 | 0.72 | GRM4 (0.55) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |