Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553674 | 0.79 | P2RY1 (0.37) | SMN1; SMN2ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL8551683 | 0.76 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL1848089 | 0.75 | JAK2 (0.48) | ALDH1A1MAPTHPGDADORA2AADORA1 | |
| SCHEMBL1849827 | 0.74 | ADORA2A (0.49) | ALDH1A1MAPTHPGDADORA2AADORA1 | |
| SCHEMBL1848064 | 0.73 | ADORA2A (0.63) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL1846481 | 0.73 | ADORA2A (0.48) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL1850792 | 0.73 | RAB9A (0.48) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL1847935 | 0.73 | ADORA2A (0.62) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL1849337 | 0.72 | ADORA3 (0.57) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL8553290 | 0.72 | LRRK2 (0.49) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |