Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551449 | 0.81 | GRM4 (0.55) | RAB9ANPC1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8551758 | 0.78 | CASP3 (0.51) | RAB9ANPC1RXFP1NPSR1ALDH1A1 | |
| SCHEMBL8556231 | 0.77 | RAB9A (0.51) | RAB9ANPC1NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8553674 | 0.77 | P2RY1 (0.37) | ALDH1A1SMN1; SMN2KMT2AMAPTADORA2A | |
| SCHEMBL8553286 | 0.76 | CNR1 (0.54) | RAB9ANPC1RXFP1NPSR1ALDH1A1 | |
| SCHEMBL8554523 | 0.76 | GLA (0.42) | RAB9ANPSR1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8553127 | 0.75 | MEN1 (0.39) | NPSR1ALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL12195699 | 0.75 | RIPK1 (0.36) | RAB9ANPC1RXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8551683 | 0.74 | SMN1; SMN2 (0.41) | RAB9ANPC1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL18230311 | 0.72 | STAT3 (0.47) | ALDH1A1SMN1; SMN2MAPTADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |