Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551683 | 0.81 | SMN1; SMN2 (0.41) | P2RY1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL8552542 | 0.79 | RAB9A (0.47) | ADORA2AALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL8553290 | 0.77 | LRRK2 (0.49) | ADORA2AALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL9892348 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MEN1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL8555203 | 0.76 | P2RY1 (0.43) | P2RY1ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL9224524 | 0.76 | P2RY1 (0.43) | P2RY1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8551758 | 0.75 | CASP3 (0.51) | P2RY1ALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL8551449 | 0.75 | GRM4 (0.55) | P2RY1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12195699 | 0.74 | RIPK1 (0.36) | P2RY1ADORA2AALDH1A1MEN1KMT2A | |
| SCHEMBL8556231 | 0.74 | RAB9A (0.51) | ALDH1A1MEN1HPGDKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |