Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 6/20 | 0.36 |
| ▸ | MAP1LC3A | Q9H492 | 6/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP5 | Q96HI0 | 6/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 6/20 | 0.34 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL8550421 | 0.84 | MAP1LC3B (0.41) | MAP1LC3BMAP1LC3AMAPT | |
| Cadaverine Tartrate SCHEMBL8189789 | 0.84 | HTR1F (0.51) | MAP1LC3BMAP1LC3AMAPTSMN1; SMN2 | |
| SCHEMBL8552249 | 0.73 | F2R (0.43) | MAPTKDM4E | |
| SCHEMBL8551467 | 0.68 | GRM5 (0.36) | BRAFMAPTKDM4E | |
| Malonic Acid SCHEMBL8548925 | 0.67 | HTR1F (0.47) | MAPTKDM4ESMN1; SMN2SENP5SENP2 | |
| Sulfuric Acid SCHEMBL8551754 | 0.64 | TMEM97 (0.43) | MCHR1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8551441 | 0.64 | ACKR3 (0.49) | MCHR1MAPTSENP5SENP2SENP1 | |
| SCHEMBL15676754 | 0.64 | NPC1 (0.61) | MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL12228481 | 0.63 | HDAC1 (0.61) | KDM4ESMN1; SMN2 | |
| SCHEMBL15676738 | 0.63 | MEN1 (0.74) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |