Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547713 | 0.83 | — | — | |
| SCHEMBL10696215 | 0.67 | HSP90AA1 (0.43) | ALDH1A1KDM4ETP53KMT2A | |
| SCHEMBL8924655 | 0.66 | MKNK1 (0.39) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8525560 | 0.62 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8820735 | 0.61 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19KDM4E | |
| SCHEMBL9237639 | 0.59 | MAOB (0.44) | KMT2A | |
| SCHEMBL8820721 | 0.59 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19KDM4E | |
| SCHEMBL6802264 | 0.59 | BCAT2 (0.42) | ALDH1A1SMN1; SMN2KDM4EMEN1MAPT | |
| SCHEMBL23415041 | 0.58 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19KDM4E | |
| SCHEMBL8818440 | 0.57 | BCAT1 (0.50) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815106-A1 | 3-ARYLURACILS AND INTERMEDIATES FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-07 | — | — | EP | disclosed |