Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551565 | 0.88 | KMT2A (0.42) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8549262 | 0.86 | ALDH1A1 (0.41) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8547763 | 0.82 | ADORA2A (0.38) | ESR1MAPTALDH1A1SMN1; SMN2THRB | |
| SCHEMBL8551133 | 0.79 | NR1H2 (0.42) | ESR1MAPTADORA2AADORA1 | |
| SCHEMBL1268020 | 0.77 | ESR1 (0.49) | ESR1MAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8552712 | 0.77 | ENPP1 (0.38) | CYP3A4CYP2C19CYP2C9ADORA2AADORA1 | |
| SCHEMBL8554002 | 0.75 | PLAU (0.44) | ESR1MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8546655 | 0.75 | MAPK1 (0.42) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8549331 | 0.74 | HSD11B1 (0.42) | MAPTALDH1A1CYP1A2SMN1; SMN2KMT2A | |
| SCHEMBL8553998 | 0.73 | KDR (0.37) | MAPTALDH1A1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |