Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 12/20 | 0.42 |
| ▸ | MMP9 | P14780 | 12/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552412 | 0.80 | MMP3 (0.40) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL27491360 | 0.79 | MMP8 (0.69) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL8551083 | 0.79 | MMP3 (0.44) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL8550568 | 0.77 | MMP3 (0.52) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL8554743 | 0.75 | MMP3 (0.51) | MMP3MMP8MMP2MMP9CHRM2 | |
| SCHEMBL8551231 | 0.71 | MMP3 (0.52) | MMP3MMP8MMP2MMP9HSD11B1 | |
| SCHEMBL8550165 | 0.68 | MMP8 (0.45) | MMP3MMP8MMP2MMP9CHRM2 | |
| SCHEMBL8551269 | 0.66 | MMP8 (0.49) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL8551832 | 0.65 | MMP8 (0.65) | MMP3MMP8MMP2MMP9 | |
| SCHEMBL743982 | 0.64 | OPRM1 (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869947-A1 | NEW BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023465-A1 | NEW BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-07-03 | — | — | WO | disclosed |