Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 7/20 | 0.40 |
| ▸ | MMP9 | P14780 | 7/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551910 | 0.79 | MMP3 (0.46) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL27491360 | 0.76 | MMP8 (0.69) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL8552412 | 0.74 | MMP3 (0.40) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL8550568 | 0.71 | MMP3 (0.52) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL8551231 | 0.69 | MMP3 (0.52) | MMP3MMP8MMP2MMP9 | |
| SCHEMBL9283554 | 0.68 | CNR1 (0.37) | PDE10ALMNABCHEACHE | |
| SCHEMBL2631079 | 0.66 | HRH3 (0.65) | PDE10AKDM4E | |
| SCHEMBL8550165 | 0.65 | MMP8 (0.45) | MMP3MMP8MMP2MMP9 | |
| SCHEMBL8551269 | 0.63 | MMP8 (0.49) | MMP3MMP8MMP2MMP9BRD4 | |
| SCHEMBL14939855 | 0.63 | NPSR1 (0.65) | MMP2MMP9LMNAKDM4EADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869947-A1 | NEW BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023465-A1 | NEW BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-07-03 | — | — | WO | disclosed |