Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 9/20 | 0.41 |
| ▸ | MMP2 | P08253 | 8/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554517 | 0.86 | HSD11B1 (0.40) | MMP8MMP3MMP9MMP2 | |
| SCHEMBL8550819 | 0.83 | MMP2 (0.45) | MMP8MMP9MMP2MMP13 | |
| SCHEMBL27491360 | 0.75 | MMP8 (0.69) | MMP8MMP3MMP9MMP2MMP13 | |
| SCHEMBL8551910 | 0.68 | MMP3 (0.46) | MMP8MMP3MMP9MMP2CHRM2 | |
| SCHEMBL5448618 | 0.68 | MMP9 (0.64) | MMP8MMP9MMP2MMP13ALDH1A1 | |
| SCHEMBL16865428 | 0.67 | MMP9 (0.56) | MMP8MMP3MMP9MMP2MMP13 | |
| SCHEMBL7483664 | 0.66 | MMP2 (0.54) | MMP8MMP9MMP2MMP13ALDH1A1 | |
| SCHEMBL8551083 | 0.65 | MMP3 (0.44) | MMP8MMP3MMP9MMP2 | |
| SCHEMBL23301176 | 0.65 | MMP13 (0.55) | MMP8MMP9MMP2MMP13ALDH1A1 | |
| SCHEMBL8551231 | 0.65 | MMP3 (0.52) | MMP8MMP3MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1318406-C | New barbituric acid derivatives, processes for their prodn. and pharmaceutical agent contg. same | BOEHRINGER MANNHEIM GMBH (DE) | 2007-05-30 | — | — | CN | disclosed |
| EP-0869947-A1 | NEW BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997023465-A1 | NEW BARBITURIC ACID DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-07-03 | — | — | WO | disclosed |