Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.73 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556342 | 0.93 | PTGS2 (0.72) | PTGS2PTGS1TP53LMNASMN1; SMN2 | |
| SCHEMBL8552523 | 0.88 | PTGS2 (0.66) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8553129 | 0.88 | PTGS2 (0.66) | PTGS2PTGS1LMNASMN1; SMN2FPR1 | |
| SCHEMBL8550834 | 0.88 | PTGS2 (0.66) | PTGS2PTGS1LMNASMN1; SMN2FPR1 | |
| SCHEMBL8554553 | 0.88 | PTGS2 (0.66) | PTGS2PTGS1LMNAFPR1 | |
| SCHEMBL8559075 | 0.86 | PTGS2 (0.63) | PTGS2PTGS1LMNASMN1; SMN2FPR1 | |
| SCHEMBL8554850 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8552699 | 0.80 | PTGS1 (0.55) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8551424 | 0.80 | PTGS1 (0.65) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL8554538 | 0.80 | PTGS1 (0.54) | PTGS2PTGS1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |