Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | FPR1 | P21462 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556342 | 0.92 | PTGS2 (0.72) | PTGS2PTGS1FPR1KMT2AALDH1A1 | |
| SCHEMBL8555698 | 0.90 | PTGS1 (0.59) | PTGS2PTGS1MMP1MMP2MMP9 | |
| SCHEMBL8550834 | 0.87 | PTGS2 (0.66) | PTGS2PTGS1FPR1ALDH1A1MAPT | |
| SCHEMBL8552523 | 0.87 | PTGS2 (0.66) | PTGS2PTGS1FPR1KMT2AALDH1A1 | |
| SCHEMBL8553129 | 0.87 | PTGS2 (0.66) | PTGS2PTGS1FPR1KMT2AALDH1A1 | |
| SCHEMBL8554553 | 0.87 | PTGS2 (0.66) | PTGS2PTGS1FPR1LMNA | |
| SCHEMBL8551988 | 0.86 | PTGS2 (0.73) | PTGS2PTGS1PKMFPR1KMT2A | |
| SCHEMBL8551389 | 0.83 | PTGS1 (0.51) | PTGS2PTGS1PKMKMT2AALDH1A1 | |
| SCHEMBL8552699 | 0.80 | PTGS1 (0.55) | PTGS2PTGS1FPR1KMT2AALDH1A1 | |
| SCHEMBL8554538 | 0.80 | PTGS1 (0.54) | PTGS2PTGS1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |