Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10795286 | 0.87 | KMT2A (0.57) | ALDH1A1KCNH2LMNAMEN1KMT2A | |
| SCHEMBL10680817 | 0.83 | CYP3A4 (0.67) | ALDH1A1KCNH2LMNAMEN1KMT2A | |
| SCHEMBL10682648 | 0.82 | LMNA (0.49) | ALDH1A1KCNH2LMNAMEN1KMT2A | |
| SCHEMBL10676648 | 0.82 | ADRA1A (0.73) | ALDH1A1KCNH2LMNAMEN1KMT2A | |
| SCHEMBL10684438 | 0.80 | CYP3A4 (0.58) | ALDH1A1KCNH2LMNAMEN1KMT2A | |
| SCHEMBL2327539 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KCNH2LMNAMEN1KMT2A | |
| SCHEMBL10680876 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KCNH2LMNAMEN1KMT2A | |
| SCHEMBL8554585 | 0.79 | RXRA (0.43) | LMNACYP3A4ADRA1ADRD3SLC29A1 | |
| SCHEMBL22407669 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KCNH2LMNAMEN1KMT2A | |
| Cadaverine Tartrate SCHEMBL10675929 | 0.78 | ADRA1A (0.68) | ALDH1A1KCNH2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | disclosed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | disclosed |