Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8595841 | 0.92 | TSHR (0.44) | ALDH1A1SMN1; SMN2TSHRPPARG | |
| SCHEMBL8556732 | 0.90 | SIRT2 (0.41) | ALDH1A1SMN1; SMN2TSHRSIRT2SIRT1 | |
| SCHEMBL8552816 | 0.88 | PPARG (0.46) | PPARG | |
| SCHEMBL8555598 | 0.86 | SIRT2 (0.43) | ALDH1A1SMN1; SMN2TSHRSIRT2SIRT1 | |
| SCHEMBL8551158 | 0.86 | TSHR (0.38) | ALDH1A1SMN1; SMN2TSHRL3MBTL1SIRT2 | |
| SCHEMBL7465812 | 0.82 | TSHR (0.41) | ALDH1A1SMN1; SMN2TSHRL3MBTL1LMNA | |
| SCHEMBL8555937 | 0.81 | TSHR (0.48) | ALDH1A1SMN1; SMN2TSHRL3MBTL1LMNA | |
| SCHEMBL8557727 | 0.80 | GSK3B (0.47) | GSK3BADKALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8555223 | 0.78 | LMNA (0.36) | ALDH1A1SMN1; SMN2TSHRL3MBTL1LMNA | |
| SCHEMBL7470317 | 0.78 | TSHR (0.38) | TSHRPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |