Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HCN1 | O60741 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554881 | 0.90 | ALDH1A1 (0.35) | RAB9ALMNATHRBSCN9ASCN5A | |
| SCHEMBL8554926 | 0.80 | HSP90AA1 (0.42) | RAB9ALMNATHRBSCN9ASCN5A | |
| SCHEMBL8556303 | 0.77 | RAB9A (0.38) | RAB9ALMNATHRBSCN9ASCN5A | |
| SCHEMBL8554050 | 0.77 | RAB9A (0.42) | RAB9ALMNATHRBALDH1A1CHRNA7 | |
| SCHEMBL9770616 | 0.75 | ALDH1A1 (0.44) | RAB9ALMNAALDH1A1HTTMEN1 | |
| SCHEMBL8555066 | 0.75 | CTSB (0.45) | RAB9ALMNATHRBCHRNA7MEN1 | |
| SCHEMBL8555791 | 0.74 | MAPT (0.47) | RAB9ALMNATHRBALDH1A1HTT | |
| SCHEMBL8553639 | 0.73 | TDP1 (0.44) | RAB9ALMNATHRBSCN9ASCN5A | |
| SCHEMBL8552834 | 0.71 | NPC1 (0.31) | RAB9ALMNAALDH1A1HTT | |
| SCHEMBL8554676 | 0.69 | RAB9A (0.40) | RAB9ALMNATHRBALDH1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |