Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552830 | 0.90 | RAB9A (0.37) | ALDH1A1SCN5ASCN9ARAB9ALMNA | |
| SCHEMBL8555094 | 0.78 | HRH3 (0.38) | ALDH1A1PKMSMN1; SMN2SCN5ASCN9A | |
| SCHEMBL8556050 | 0.76 | CTSB (0.43) | ALDH1A1PKMSMN1; SMN2LMNAMAPT | |
| SCHEMBL8967939 | 0.76 | KAT2B (0.50) | ALDH1A1PKMSMN1; SMN2RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL8968053 | 0.74 | KAT2B (0.51) | ALDH1A1PKMSMN1; SMN2RAB9ALMNA | |
| SCHEMBL9770616 | 0.74 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL8554926 | 0.70 | HSP90AA1 (0.42) | ALDH1A1SCN5ASCN9ARAB9ALMNA | |
| SCHEMBL8552834 | 0.69 | NPC1 (0.31) | ALDH1A1SMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL8967649 | 0.69 | CA12 (0.49) | ALDH1A1SMN1; SMN2MAPTGAAHPGD | |
| Fumaric Acid SCHEMBL8968115 | 0.69 | NPC1 (0.43) | ALDH1A1PKMSMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |