Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556935 | 0.88 | ALDH1A1 (0.48) | LMNAMEN1KMT2ACYP3A4MLNR | |
| SCHEMBL8558360 | 0.80 | RXRA (0.50) | LMNAMEN1KMT2ACYP3A4MLNR | |
| SCHEMBL8555057 | 0.75 | NR4A2 (0.51) | LMNAMEN1KMT2ACYP3A4MLNR | |
| SCHEMBL2327539 | 0.73 | ALDH1A1 (0.64) | LMNAMEN1KMT2ACYP3A4MLNR | |
| SCHEMBL8552887 | 0.72 | NR4A2 (0.47) | LMNAMEN1KMT2ACYP3A4MLNR | |
| SCHEMBL4499708 | 0.72 | LMNA (0.61) | LMNAMEN1KMT2ACYP3A4MLNR | |
| SCHEMBL4500966 | 0.71 | MEN1 (0.72) | LMNAMEN1KMT2ACYP3A4MLNR | |
| SCHEMBL6277857 | 0.71 | MEN1 (0.65) | LMNAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL8556067 | 0.71 | CACNA1G (0.51) | LMNAMEN1KMT2ACYP3A4MLNR | |
| SCHEMBL8556384 | 0.70 | MEN1 (0.60) | LMNAMEN1KMT2ACYP3A4MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |