Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551449 | 0.79 | GRM4 (0.55) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL8551758 | 0.77 | CASP3 (0.51) | SMN1; SMN2NPSR1ALDH1A1KDM4ERXFP1 | |
| SCHEMBL8553674 | 0.73 | P2RY1 (0.37) | SMN1; SMN2ALDH1A1KMT2AMAPTADORA2A | |
| SCHEMBL8556231 | 0.71 | RAB9A (0.51) | SMN1; SMN2NPSR1ALDH1A1KDM4ENPC1 | |
| SCHEMBL23911661 | 0.71 | ADORA2A (0.42) | ALDH1A1ADORA2A | |
| SCHEMBL14808194 | 0.70 | CNR1 (1.00) | CNR1SMN1; SMN2NPSR1ALDH1A1KDM4E | |
| SCHEMBL8551683 | 0.70 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL20481554 | 0.68 | P2RY1 (0.39) | SMN1; SMN2NPSR1MAPK9MAPK10ALDH1A1 | |
| SCHEMBL8554523 | 0.68 | GLA (0.42) | SMN1; SMN2NPSR1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8551763 | 0.68 | P2RY1 (0.34) | ALDH1A1KMT2AADORA2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |