Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553290 | 0.71 | LRRK2 (0.49) | ADORA2AMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8553674 | 0.71 | P2RY1 (0.37) | P2RY1ADORA2AMEN1ALDH1A1HPGD | |
| SCHEMBL8552542 | 0.71 | RAB9A (0.47) | ADORA2AMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8551683 | 0.70 | SMN1; SMN2 (0.41) | P2RY1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL20481554 | 0.70 | P2RY1 (0.39) | P2RY1ADORA2AMEN1ALDH1A1KMT2A | |
| SCHEMBL8551758 | 0.70 | CASP3 (0.51) | P2RY1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8556231 | 0.69 | RAB9A (0.51) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8553127 | 0.67 | MEN1 (0.39) | P2RY1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8555203 | 0.66 | P2RY1 (0.43) | P2RY1ALDH1A1HPGDKMT2A | |
| SCHEMBL8554523 | 0.66 | GLA (0.42) | MEN1ALDH1A1HPGDKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |