Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 13/20 | 0.50 |
| ▸ | NPC1 | O15118 | 11/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680901 | 0.81 | CASP3 (0.54) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL6680361 | 0.81 | RAB9A (0.55) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL8551449 | 0.79 | GRM4 (0.55) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8553290 | 0.78 | LRRK2 (0.49) | RAB9ANPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL8553286 | 0.77 | CNR1 (0.54) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8553674 | 0.75 | P2RY1 (0.37) | SMN1; SMN2HPGDKMT2AMEN1MAPT | |
| SCHEMBL12195699 | 0.73 | RIPK1 (0.36) | CASP3SENP8SENP7SENP6RAB9A | |
| SCHEMBL8556231 | 0.73 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL8551683 | 0.72 | SMN1; SMN2 (0.41) | RAB9ANPC1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL8552542 | 0.70 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |