Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 7/20 | 0.34 |
| ▸ | HTR1B | P28222 | 7/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553525 | 0.86 | DRD2 (0.43) | DRD2SLC6A4HTR1DHTR1BNPC1 | |
| SCHEMBL8552196 | 0.86 | HTR1D (0.34) | DRD2SLC6A4HTR1DHTR1BMAPT | |
| SCHEMBL8549862 | 0.83 | DRD2 (0.38) | DRD2SLC6A4 | |
| SCHEMBL7481585 | 0.83 | HTR1D (0.54) | DRD2HTR1DHTR1BHTR1AHTR1F | |
| SCHEMBL8552293 | 0.80 | LMNA (0.42) | DRD2SLC6A4HTR1DHTR1BCYP2C19 | |
| SCHEMBL8704365 | 0.79 | DRD2 (0.42) | DRD2SLC6A4HTR1DHTR1BNPC1 | |
| SCHEMBL8548010 | 0.77 | DRD2 (0.40) | DRD2SLC6A4HTR1DHTR1BHPGD | |
| SCHEMBL8723972 | 0.76 | HRH3 (0.35) | DRD2SLC6A4HTR1DHTR1BSMN1; SMN2 | |
| SCHEMBL8703198 | 0.76 | DRD2 (0.34) | DRD2SLC6A4 | |
| SCHEMBL8553071 | 0.75 | KMT2A (0.47) | NPC1RAB9ASMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |