Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281848 | 0.88 | MAPT (0.37) | CTSBARMAPTALDH1A1MAPK1 | |
| SCHEMBL8967666 | 0.86 | ALDH1A1 (0.45) | CTSBARMAPTALDH1A1MAPK1 | |
| SCHEMBL8967681 | 0.85 | SIGMAR1 (0.40) | ARMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8555244 | 0.82 | CTSB (0.39) | CTSBARMAPTALDH1A1MAPK1 | |
| SCHEMBL8967617 | 0.77 | TUBB3 (0.38) | MAPTALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8968120 | 0.76 | SLC6A3 (0.42) | ALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL8967753 | 0.74 | SIGMAR1 (0.41) | ARMAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL8555066 | 0.74 | CTSB (0.45) | CTSBARMAPTSMN1; SMN2TDP1 | |
| SCHEMBL8967712 | 0.73 | MAPT (0.47) | ARMAPTALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8556050 | 0.72 | CTSB (0.43) | CTSBARMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |