Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.46 |
| ▸ | CCR9 | P51686 | 1/20 | 0.45 |
| ▸ | NAT1 | P18440 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555077 | 0.87 | PTGS2 (0.51) | HSD11B1POLBKDM4ERXFP1MAPT | |
| SCHEMBL8560337 | 0.81 | MAPT (0.50) | KDM1AALDH1A1POLBKDM4ERXFP1 | |
| SCHEMBL8557604 | 0.76 | AR (0.51) | KDM1AALDH1A1POLBKDM4ERXFP1 | |
| SCHEMBL8474456 | 0.75 | EDNRB (0.58) | KDM1AHSD11B1ALDH1A1KDM4EMAPT | |
| SCHEMBL8560630 | 0.74 | MAPT (0.49) | HSD11B1ALDH1A1KDM4ERXFP1GAA | |
| SCHEMBL8560574 | 0.73 | MAPT (0.46) | HSD11B1ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL8555985 | 0.72 | NR4A2 (0.54) | HSD11B1ALDH1A1POLBKDM4ERXFP1 | |
| SCHEMBL8554937 | 0.72 | MAPT (0.44) | HSD11B1ALDH1A1KDM4ERXFP1MAPT | |
| SCHEMBL8633966 | 0.72 | KDM1A (0.49) | KDM1AHSD11B1ALDH1A1POLBKDM4E | |
| SCHEMBL8555624 | 0.72 | MAPT (0.58) | ALDH1A1POLBKDM4ERXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |