Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555295 | 0.96 | NR4A2 (0.36) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL8557664 | 0.90 | L3MBTL1 (0.43) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL8556320 | 0.90 | GRM2 (0.42) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL8556827 | 0.89 | GRM2 (0.42) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL8559042 | 0.88 | L3MBTL1 (0.43) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL8560691 | 0.88 | CA1 (0.41) | CA12CA1CA2CA9RXRA | |
| SCHEMBL8555966 | 0.87 | CA12 (0.37) | CA12CA1CA2CA9RXRA | |
| SCHEMBL8556401 | 0.87 | CYP2C9 (0.40) | CA12CA1CA2CA9RXRA | |
| SCHEMBL8553428 | 0.87 | CA1 (0.42) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL7505602 | 0.86 | CA2 (0.42) | CA12CA1CA2CA9RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |