Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559042 | 0.96 | L3MBTL1 (0.43) | L3MBTL1CA1CA2CA9CA13 | |
| SCHEMBL8560691 | 0.92 | CA1 (0.41) | L3MBTL1CA1CA2CA9CA13 | |
| SCHEMBL8553428 | 0.91 | CA1 (0.42) | L3MBTL1CA1CA2CA9CA13 | |
| SCHEMBL8556320 | 0.90 | GRM2 (0.42) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL8557954 | 0.90 | RXRA (0.47) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL8560882 | 0.90 | MAPT (0.43) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL8554223 | 0.90 | GPR55 (0.36) | CA1CA2CA9MAPTALDH1A1 | |
| SCHEMBL8560978 | 0.90 | CDK9 (0.42) | CA1CA2CA9SMN1; SMN2RXRA | |
| SCHEMBL8556827 | 0.90 | GRM2 (0.42) | CA1CA2CA9CA13MAPT | |
| SCHEMBL8555295 | 0.88 | NR4A2 (0.36) | CA1CA2CA9MAPTRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |