Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556827 | 0.97 | GRM2 (0.42) | GRM2F10GPR55ALOX5APFEN1 | |
| SCHEMBL8557664 | 0.90 | L3MBTL1 (0.43) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL8554223 | 0.90 | GPR55 (0.36) | F10GPR55CA12CA1CA2 | |
| SCHEMBL8559042 | 0.89 | L3MBTL1 (0.43) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL8560691 | 0.89 | CA1 (0.41) | CA12CA1CA2CA9RXRA | |
| SCHEMBL8559362 | 0.88 | ALOX5AP (0.40) | GRM2ALOX5APFEN1RXRARXRB | |
| SCHEMBL8560601 | 0.88 | ALOX5AP (0.41) | ALOX5APFEN1CA12CA1CA2 | |
| SCHEMBL8555295 | 0.88 | NR4A2 (0.36) | F10GPR55CA12CA1CA2 | |
| SCHEMBL8553428 | 0.87 | CA1 (0.42) | GPR55CA12CA1CA2CA9 | |
| SCHEMBL7510970 | 0.87 | PTGS2 (0.43) | GRM2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |