Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8834199 | 0.87 | GPBAR1 (0.55) | CYSLTR1CYSLTR2ALOX5APALOX5GPBAR1 | |
| SCHEMBL8834730 | 0.83 | PDE10A (0.48) | CYSLTR1CYSLTR2ALOX5APALOX5GPBAR1 | |
| SCHEMBL8557729 | 0.79 | PDE10A (0.43) | CYSLTR1CYSLTR2ALOX5APALOX5GPBAR1 | |
| SCHEMBL8922390 | 0.76 | ALOX5AP (0.41) | CYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL8835183 | 0.76 | PARP10 (0.50) | ALOX5APALOX5 | |
| SCHEMBL8560309 | 0.75 | KCNH2 (0.39) | GPBAR1 | |
| SCHEMBL8559981 | 0.74 | PARP10 (0.39) | — | |
| SCHEMBL8557960 | 0.73 | GRM5 (0.41) | ALOX5APALOX5 | |
| SCHEMBL9054127 | 0.72 | FFAR1 (0.55) | CYSLTR1CYSLTR2ALOX5APALOX5GPBAR1 | |
| SCHEMBL8559028 | 0.71 | PDE10A (0.45) | ALOX5APALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |