Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835183 | 0.84 | PARP10 (0.50) | ALOX5ALOX5APKDM4ENPC1ALDH1A1 | |
| SCHEMBL8560309 | 0.82 | KCNH2 (0.39) | GRM5KDM4ENPC1ALDH1A1POLB | |
| SCHEMBL8557729 | 0.81 | PDE10A (0.43) | ALOX5ALOX5APKDM4ENPC1MAPT | |
| SCHEMBL8834199 | 0.80 | GPBAR1 (0.55) | ALOX5ALOX5AP | |
| SCHEMBL8559969 | 0.77 | PPARD (0.49) | ALOX5KDM4ENPC1POLBMAPT | |
| SCHEMBL8559981 | 0.76 | PARP10 (0.39) | KDM4ENPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL8559028 | 0.73 | PDE10A (0.45) | ALOX5ALOX5APNPC1POLBMAPT | |
| SCHEMBL8557961 | 0.70 | MAPT (0.42) | ALOX5KDM4ENPC1ALDH1A1POLB | |
| SCHEMBL8559076 | 0.69 | KMT2A (0.40) | GRM5ALOX5ALOX5APKDM4EALDH1A1 | |
| SCHEMBL5383088 | 0.69 | CYSLTR1 (0.56) | GRM5ALOX5ALOX5APKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |