Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 5/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559981 | 0.88 | PARP10 (0.39) | PARP10ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8557960 | 0.84 | GRM5 (0.41) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL8557729 | 0.83 | PDE10A (0.43) | SMN1; SMN2KDM4ENPC1RAB9ACYP2C9 | |
| SCHEMBL8560309 | 0.83 | KCNH2 (0.39) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL8834199 | 0.82 | GPBAR1 (0.55) | ALOX5ALOX5AP | |
| SCHEMBL8559028 | 0.77 | PDE10A (0.45) | NPC1RAB9AALOX5ALOX5APKCNH2 | |
| SCHEMBL8559969 | 0.75 | PPARD (0.49) | SMN1; SMN2KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL25433706 | 0.72 | PARP10 (0.53) | PARP10ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL25381933 | 0.70 | PARP10 (0.57) | PARP10ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL2089763 | 0.70 | PARP10 (0.73) | PARP10ALDH1A1SMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668146-A | ANTIINFLAMMATORY AGENTS OR ANTIALLERGENS | ABBOTT LABORATORIES (US) | 1997-09-16 | — | — | US | claimed |
| US-5668146-A | ANTIINFLAMMATORY AGENTS OR ANTIALLERGENS | ABBOTT LABORATORIES (US) | 1997-09-16 | — | — | US | disclosed |