Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 7/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557729 | 0.81 | PDE10A (0.43) | PDE10AALOX5MAPTLMNAALOX5AP | |
| SCHEMBL8834199 | 0.80 | GPBAR1 (0.55) | PDE10AALOX5ALOX5APAKR1B1 | |
| SCHEMBL8552848 | 0.76 | SMPD1 (0.36) | MAPTLMNAPOLBNPC1RAB9A | |
| SCHEMBL8559981 | 0.73 | PARP10 (0.39) | PDE10ANPC1MEN1KMT2AKCNH2 | |
| SCHEMBL8557960 | 0.73 | GRM5 (0.41) | ALOX5MAPTALOX5APPOLBNPC1 | |
| SCHEMBL8559969 | 0.73 | PPARD (0.49) | ALOX5MAPTPOLBNPC1RAB9A | |
| SCHEMBL10547054 | 0.72 | NPC1 (0.59) | PDE10AALOX5MAPTLMNAPOLB | |
| SCHEMBL7547340 | 0.72 | MEN1 (0.60) | PDE10AMAPTLMNAPOLBNPC1 | |
| SCHEMBL8557961 | 0.72 | MAPT (0.42) | ALOX5MAPTLMNAPOLBNPC1 | |
| SCHEMBL8555063 | 0.71 | CYSLTR1 (0.42) | ALOX5ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |