Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560309 | 0.89 | KCNH2 (0.39) | PDE10ANPC1FFAR1KCNH2KDM4E | |
| SCHEMBL8835183 | 0.88 | PARP10 (0.50) | PARP10MAPK14SMOSMN1; SMN2NPC1 | |
| SCHEMBL8557961 | 0.84 | MAPT (0.42) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL8834199 | 0.81 | GPBAR1 (0.55) | PDE10AFFAR1 | |
| SCHEMBL8557729 | 0.79 | PDE10A (0.43) | PDE10AKMT2ASMN1; SMN2NPC1FFAR1 | |
| SCHEMBL8557960 | 0.76 | GRM5 (0.41) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| SCHEMBL8559969 | 0.75 | PPARD (0.49) | MEN1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL8559028 | 0.73 | PDE10A (0.45) | PDE10AMEN1KMT2ANPC1KCNH2 | |
| SCHEMBL8559814 | 0.71 | PARP10 (0.45) | PARP10PDE10AMAPK14SMOMEN1 | |
| SCHEMBL8559850 | 0.68 | MEN1 (0.42) | PARP10PDE10AMAPK14SMOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |