Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559481 | 0.88 | ALDH1A1 (0.40) | MAPTALDH1A1POLBLMNACCR4 | |
| SCHEMBL8559341 | 0.88 | MAPT (0.44) | MAPTALDH1A1LMNAKDM4ERXFP1 | |
| SCHEMBL8555536 | 0.87 | ALDH1A1 (0.42) | MAPTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL8555914 | 0.85 | MAPT (0.43) | MAPTALDH1A1POLBLMNACCR4 | |
| SCHEMBL8559800 | 0.85 | SLC40A1 (0.45) | MAPTALDH1A1POLBLMNACCR4 | |
| SCHEMBL8555336 | 0.84 | MAPT (0.44) | MAPTALDH1A1POLBLMNACCR4 | |
| SCHEMBL8555983 | 0.84 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAKDM4EGGT1 | |
| SCHEMBL8555293 | 0.83 | PIK3CG (0.43) | MAPTALDH1A1POLBLMNAKDM4E | |
| SCHEMBL8560392 | 0.83 | MAPT (0.44) | MAPTALDH1A1LMNAKDM4ERXFP1 | |
| SCHEMBL8556141 | 0.82 | KAT6A (0.46) | MAPTALDH1A1POLBLMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |