Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558700 | 0.92 | PGR (0.46) | FBP1ALDH1A1MAPTLMNAPGR | |
| SCHEMBL8556712 | 0.90 | MAPT (0.42) | ALDH1A1MAPTLMNAPGRKDM4E | |
| SCHEMBL8553814 | 0.90 | MAPT (0.45) | FBP1ALDH1A1MAPTLMNAPGR | |
| SCHEMBL8559341 | 0.89 | MAPT (0.44) | FBP1ALDH1A1MAPTLMNAPGR | |
| SCHEMBL8555293 | 0.87 | PIK3CG (0.43) | ALDH1A1MAPTLMNAPGRKDM4E | |
| SCHEMBL8556141 | 0.87 | KAT6A (0.46) | FBP1ALDH1A1MAPTLMNAPGR | |
| SCHEMBL8560337 | 0.84 | MAPT (0.50) | FBP1ALDH1A1MAPTLMNAPGR | |
| SCHEMBL8556146 | 0.84 | PGR (0.50) | FBP1ALDH1A1MAPTLMNAPGR | |
| SCHEMBL8556039 | 0.84 | MAPT (0.44) | FBP1ALDH1A1MAPTLMNAPGR | |
| SCHEMBL8556399 | 0.83 | MAPT (0.49) | FBP1ALDH1A1MAPTLMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0699192-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994027980-A1 | SUBSTITUTED OXAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1994-12-08 | — | — | WO | disclosed |