Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552979 | 0.82 | NPC1 (0.41) | PIK3CD | |
| SCHEMBL8550682 | 0.79 | DGAT2 (0.44) | CHEK2DGAT2 | |
| SCHEMBL8551914 | 0.78 | PARP1 (0.39) | CHEK2 | |
| SCHEMBL8555474 | 0.77 | DGAT2 (0.36) | DGAT2 | |
| SCHEMBL8556963 | 0.76 | DGAT2 (0.41) | PRMT5DGAT2 | |
| SCHEMBL8552606 | 0.76 | DGAT2 (0.43) | CHEK2DGAT2 | |
| SCHEMBL8555907 | 0.73 | CHEK2 (0.43) | CHEK2PRMT5DGAT2 | |
| SCHEMBL8555463 | 0.73 | GPR119 (0.40) | CHEK2PRMT5DGAT2 | |
| SCHEMBL8551701 | 0.73 | DGAT2 (0.39) | CHEK2PRMT5DGAT2HCRTR1HCRTR2 | |
| SCHEMBL8620953 | 0.71 | DGAT2 (0.41) | CHEK2DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |