Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8133497 | 0.84 | SIRT1 (0.49) | PARP1CHEK1NQO1OGAHEXA | |
| SCHEMBL7985172 | 0.80 | SIRT1 (0.44) | PARP1CHEK1NQO1OGAHEXA | |
| SCHEMBL5828276 | 0.77 | PARP1 (0.51) | PARP1CHEK1NQO1HEXAHEXB | |
| SCHEMBL9622936 | 0.76 | TERT (0.52) | PARP1NQO1HEXAHEXBTERT | |
| Hydrochloric Acid SCHEMBL9622732 | 0.75 | TERT (0.51) | PARP1NQO1HEXAHEXBTERT | |
| SCHEMBL5828670 | 0.73 | PARP1 (0.59) | PARP1ROCK2SIRT1KDM4EADORA3 | |
| SCHEMBL9622806 | 0.72 | NQO1 (0.67) | PARP1CHEK1NQO1KDM4EADORA3 | |
| SCHEMBL8560926 | 0.71 | PARP1 (0.39) | PARP1BCHEACHECHEK1NQO1 | |
| SCHEMBL6229657 | 0.67 | PRKCA (0.63) | PARP1CHEK1NQO1ROCK2KDM4E | |
| SCHEMBL8138008 | 0.66 | HEXA (0.58) | OGAHEXAHEXBTERTDYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820985-A1 | Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-01-28 | — | — | EP | disclosed |