Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | PTGES | O14684 | 5/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556539 | 0.90 | MAPT (0.42) | ALDH1A1MAPTHTTPOLBLMNA | |
| SCHEMBL8553385 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPTHTTPOLBLMNA | |
| SCHEMBL8555334 | 0.87 | MAPT (0.46) | ALDH1A1MAPTHTTPOLBLMNA | |
| SCHEMBL8554394 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTHTTPOLBSMN1; SMN2 | |
| SCHEMBL8553095 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTHTTPOLBLMNA | |
| SCHEMBL8553324 | 0.79 | KDM4E (0.43) | ALDH1A1MAPTHTTLMNANPSR1 | |
| SCHEMBL1984012 | 0.76 | NTRK1 (0.48) | ALDH1A1MAPTHTTPOLBLMNA | |
| SCHEMBL8553246 | 0.74 | NTRK1 (0.39) | ALDH1A1MAPTLMNAPTGESALOX5 | |
| SCHEMBL8556278 | 0.73 | NTRK1 (0.43) | ALDH1A1MAPTHTTPOLBNPSR1 | |
| SCHEMBL8552593 | 0.70 | MAPT (0.41) | ALDH1A1MAPTLMNANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |