Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 5/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556673 | 0.89 | PTGES (0.40) | NTRK1PTGESALOX5ALDH1A1MAPT | |
| SCHEMBL8554369 | 0.88 | GAA (0.46) | NTRK1PTGESALOX5ALDH1A1MAPT | |
| SCHEMBL8553174 | 0.87 | PTGES (0.43) | NTRK1PTGESALOX5ALDH1A1MAPT | |
| SCHEMBL1984012 | 0.84 | NTRK1 (0.48) | NTRK1PTGESALOX5ALDH1A1MAPT | |
| SCHEMBL8557168 | 0.83 | GAA (0.44) | NTRK1PTGESALOX5ALDH1A1TSHR | |
| SCHEMBL7355477 | 0.82 | STS (0.40) | NTRK1PTGESALOX5ALDH1A1TSHR | |
| SCHEMBL8552075 | 0.82 | FPR1 (0.41) | NTRK1PTGESALOX5ALDH1A1MAPT | |
| SCHEMBL8552811 | 0.81 | FPR1 (0.45) | NTRK1ALDH1A1TSHRLMNAL3MBTL1 | |
| SCHEMBL8556018 | 0.80 | LMNA (0.48) | NTRK1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8555582 | 0.79 | LMNA (0.47) | NTRK1ALDH1A1MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |