Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555849 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MAPTNPSR1PTGESALOX5 | |
| SCHEMBL8556539 | 0.87 | MAPT (0.42) | ALDH1A1MAPTNPSR1PTGESALOX5 | |
| SCHEMBL8555334 | 0.86 | MAPT (0.46) | ALDH1A1MAPTPTGESALOX5LMNA | |
| SCHEMBL8553095 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTPTGESALOX5LMNA | |
| SCHEMBL8554394 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTHTTSMN1; SMN2POLB | |
| SCHEMBL8553364 | 0.77 | PTGES (0.49) | ALDH1A1MAPTNPSR1PTGESLMNA | |
| SCHEMBL1984012 | 0.77 | NTRK1 (0.48) | ALDH1A1MAPTPTGESALOX5LMNA | |
| SCHEMBL8556278 | 0.72 | NTRK1 (0.43) | ALDH1A1MAPTNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8554369 | 0.69 | GAA (0.46) | ALDH1A1MAPTNPSR1PTGESALOX5 | |
| SCHEMBL8550650 | 0.69 | FPR1 (0.53) | ALDH1A1LMNAHTTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |