Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 2/20 | 0.37 |
| ▸ | FLT4 | P35916 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555849 | 0.90 | ALDH1A1 (0.44) | MAPTALDH1A1POLBHTTLMNA | |
| SCHEMBL8553385 | 0.87 | ALDH1A1 (0.42) | MAPTALDH1A1POLBHTTLMNA | |
| SCHEMBL8554394 | 0.84 | ALDH1A1 (0.39) | MAPTALDH1A1POLBHTTL3MBTL1 | |
| SCHEMBL8555334 | 0.84 | MAPT (0.46) | MAPTALDH1A1POLBHTTLMNA | |
| SCHEMBL8553095 | 0.83 | ALDH1A1 (0.46) | MAPTALDH1A1POLBHTTLMNA | |
| SCHEMBL8550649 | 0.81 | NTRK1 (0.46) | ALDH1A1NTRK1HTTLMNANR3C1 | |
| SCHEMBL1984012 | 0.75 | NTRK1 (0.48) | MAPTALDH1A1NTRK1POLBHTT | |
| SCHEMBL8553324 | 0.72 | KDM4E (0.43) | MAPTALDH1A1NTRK1HTTLMNA | |
| SCHEMBL8556278 | 0.70 | NTRK1 (0.43) | MAPTALDH1A1NTRK1POLBHTT | |
| SCHEMBL8555738 | 0.69 | TDP1 (0.44) | MAPTALDH1A1NTRK1LMNANR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |