Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555849 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL8556539 | 0.84 | MAPT (0.42) | ALDH1A1MAPTSMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL8553385 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL8551978 | 0.81 | KDM4E (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8555334 | 0.80 | MAPT (0.46) | ALDH1A1MAPTKMT2AKDM4EPTGS2 | |
| SCHEMBL8553095 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1984012 | 0.71 | NTRK1 (0.48) | ALDH1A1MAPTSMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL8551939 | 0.67 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8556278 | 0.67 | NTRK1 (0.43) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8553364 | 0.65 | PTGES (0.49) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |