Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262332 | 0.83 | MEN1 (0.41) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29034429 | 0.81 | MEN1 (0.48) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL13964533 | 0.75 | LMNA (0.43) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9091483 | 0.74 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL11174842 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL27458128 | 0.71 | KMT2A (0.50) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6132790 | 0.70 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL8648702 | 0.70 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL12634965 | 0.70 | MEN1 (0.54) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL6132273 | 0.70 | KDM4E (0.54) | MEN1KMT2AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |