Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.42 |
| ▸ | RXRB | P28702 | 3/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554892 | 0.77 | NPC1 (0.39) | MAPTHSD17B10CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL27757178 | 0.73 | TSHR (0.50) | TDP1MAPTHSD17B10TP53MAPK1 | |
| SCHEMBL11131452 | 0.72 | LMNA (0.52) | TDP1MAPTHSD17B10TP53MAPK1 | |
| SCHEMBL28182671 | 0.72 | LMNA (0.61) | TDP1MAPTHSD17B10TP53CYP3A4 | |
| SCHEMBL6551409 | 0.72 | TDP1 (0.50) | TDP1MAPTHSD17B10TP53MAPK1 | |
| SCHEMBL9426280 | 0.71 | ACHE (0.48) | TDP1MAPTHSD17B10L3MBTL1RXRA | |
| SCHEMBL27510569 | 0.71 | ALDH1A1 (0.56) | TDP1MAPTSMN1; SMN2L3MBTL1RXRA | |
| SCHEMBL8556077 | 0.70 | MAPT (0.60) | TDP1MAPTHSD17B10TP53CYP3A4 | |
| SCHEMBL30942586 | 0.70 | MAPT (0.60) | TDP1MAPTHSD17B10TP53CYP3A4 | |
| SCHEMBL14042589 | 0.70 | TSHR (0.57) | TDP1MAPTHSD17B10SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767146-A | Anti-osteopathic composition | HOECHST JAPAN LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5716995-A | TREATING OR PREVENTING BONE DISEASES BY ADMINISTERING PHENOLIC, HETERO- OR NAPHTHYL- DERIVATIVES OF 1-HYDROXY-3-OXO-1-PROPENYL BENZOIC ACID TO PROMOTE OSTEOGENESIS | HOECHST JAPAN LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5703128-A | TREATING OSTEOPOROSIS, BONE FRACTURES | HOECHST JAPAN LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |