Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18073895 | 0.83 | ROCK2 (0.56) | MAPTKDM4EALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL8555826 | 0.79 | KMT2A (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7710536 | 0.78 | HDAC3 (0.46) | RXFP1MAPTMEN1KMT2ATP53 | |
| SCHEMBL8629096 | 0.78 | MAPT (0.55) | RXFP1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8554262 | 0.77 | ALDH1A1 (0.54) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL7707705 | 0.77 | SMN1; SMN2 (0.42) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8556645 | 0.77 | PARP1 (0.52) | RXFP1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL8553623 | 0.76 | ALDH1A1 (0.44) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7422734 | 0.76 | KDM4E (0.44) | RXFP1KDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL8624225 | 0.76 | ROCK2 (0.41) | MAPTKDM4EALDH1A1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |